We share with you here a nice overview of Diabetes’ situation in 2019. Compliments of the GLOBAL DIABETES 2019’s Conference in Amsterdam.
European Diabetes Market is growing rapidly. Data from the International Diabetes Federation to mark World Diabetes Day in November last year (2018) showed that there were 803,900 diabetics in the UAE, about 19 per cent of the population. Middle East Diabetes Market is expected to grow at a CAGR of 5.1% and expected to reach US$ 16.4 billion by 2023 from US$ 11.6 billion in 2016.
In countries like Saudi Arabia, Kuwait, Bahrain, Qatar and UAE, about 24%, 23%, 22%, 20% and 19% of the population is affected by this disease respectively. By 2020, an estimated 32% of the adult population (age 20-79), including both UAE nationals and expatriates, may have diabetes or prediabetes at a possible cost of $8.52 billion (USD) (AED 31.27 billion) over the next decade if current trends continue. Medical costs attributable to diabetes and prediabetes in the UAE are forecast to increase to perhaps $1.04 billion (AED 3.82 billion) by 2020, representing a 58% increase from an estimated $657 million (AED 2.41 billion) in 2010. Moreover, the UAE is also growing and is the second largest market for Middle East countries on Diabetes.
There are plenty of large and small market players which operate in the Middle East and Africa diabetes market are: Abbott (USA), Bayer AG (Germany), Becton Dickinson and Company (USA), Johnson & Johnson Services, Inc. (USA), Merck & Co., Inc. (USA), Novartis AG (Switzerland), Novo Nordisk A/S (Denmark), Roche Diabetes Care, Inc. (USA), Sanofi-Aventis U.S. LLC (US), Ypsomed (Switzerland).
Type I and Type II Diabetes
Type 1 Diabetes mellitus (otherwise called type 1 diabetes) is a type of diabetes mellitus that outcomes from the immune system annihilation of the insulin-delivering beta cells in the pancreas. The ensuing absence of insulin prompts expanded glucose in the blood and pee. The established manifestations are regular pee, expanded thirst, expanded yearning, and weight reduction. The reason for diabetes mellitus sort 1 is obscure. Type 1 diabetes can be recognized from type 2 from autoantibody testing. The C-peptide test, which measures endogenous insulin generation, can likewise be utilized.
Type 2 diabetes is a long haul metabolic turmoil that is portrayed by high glucose, insulin resistance, and relative absence of insulin. Basic side effects incorporate expanded thirst, incessant pee, and unexplained weight reduction. Indications may likewise incorporate expanded craving, feeling tired, and bruises that don’t recuperate. Regularly indications go ahead gradually. Long haul complexities from high glucose incorporate coronary illness, strokes, diabetic retinopathy which can bring about visual impairment, kidney disappointment, and poor blood stream in the appendages which may prompt removals.
Diagnosis and Treatment
Diabetes may be analysed based on plasma and glucose criteria or A1C criteria. Early in disease diabetes shows no symptoms so blood tests are used to diagnose diabetes and pre-diabetes. Clinical diagnostic in diabetes involve taking blood at a healthcare facility centre or commercial diagnostic centre and sending the sample to a lab for examination. To ensure that test results are accurate lab study of blood of required. Glucose calculating devices used in a health care provider’s office, such as finger-stick devices, are not precise enough for analysis but may be used as a rapid indicator of high blood sugar. Such area of research are highly discussed in ADA annual meeting
Endocrine and Metabolic Disorders
Clinical Endocrinology and metabolism is a field of medicine; more precisely a sub-specialty of internal medicine, which mainly deals with the investigation and management of sicknesses related to hormones. The human endocrine system involves number of glands. These glands harvest and release hormones which monitor many important function of our body. When the hormone exits the gland they reach the bloodstream and are moved to organs and tissues in every part of the body. Endocrinology also concentrates on the endocrine glands and tissues that secrete hormones. The human endocrine system comprises of several glands. These glands harvest and secrete hormones which regulate the body’s metabolism, growth, sexual development and function. Hormonal imbalance in our body henceforth leads to diabetes.
Gestational diabetes is developed during pregnancy (gestation). Like other types of diabetes, gestational diabetes affects the usage of glucose by cells. High blood sugar can be caused by gestational diabetes and this can affect the pregnancy and the health of baby. Gestational diabetes can be controlled by women by eating healthy foods, exercising and taking medication if necessary. Controlling blood sugar can prevent a difficult birth and can keep both the mother and baby healthy. In gestational diabetes, blood sugar returns to normal soon after delivery. But a person having gestational diabetes can have a risk for type 2 diabetes.
Ophthalmologic problem in Diabetes
Diabetes can also cause a group of eye conditions which are collectively called Diabetic eye disease. The most common form of the disease is diabetic retinopathy which is associated with damage to the tiny blood vessels in the retina. This condition can progress through four stages and eventually result in retinal detachment or permanent vision loss. Other forms of the diabetic eye disease include Glaucoma, Cataracts, Blindness, etc. For early detection and treatment of such disease, it is necessary for affected individuals to undergo retinopathy screening and taking proper care of oneself.
Cardiovascular risk in Diabetes
The risk of CVD mortality in type 2 diabetic patients is more than double compared with that in age-matched subjects. Stroke events and all manifestations of CHD, myocardial infarction (MI), sudden death, and angina pectoris is at least twofold more common in patients with type 2 diabetes than in non-diabetic individuals. A high proportion of patients with type 2 diabetes die after an acute MI within 1 year, and a considerable number of patients die outside the hospital. Relative risk for CHD events is higher in female patients with type 2 diabetes than in male patients with type 2 diabetes. The reason for the sex difference is largely unknown but could be at least in part explained by a heavier risk-factor burden and a greater effect of blood pressure and atherogenic dyslipidemia on the risk of CVD in diabetic women than in diabetic men.
Stem Cell treatment for Diabetes
In every of these cases, using one’s own stem cells will facilitate the exocrine gland regenerate and boost its ability to produce insulin. Procedure continues to achieve success, with patients experiencing health advantages even six months after stem cell diabetes treatment. repeated applications of adipose stem cells is that the most effective treatment for diabetes type two, providing an open window to create dietary changes, supplementation and exercise much more effective for long-term management of blood glucose. Adult stem cells, undifferentiated and adaptable, area unit ready to transform into the cells of innumerable organs and structures inside the body. Several therapies use stem cells as they will restore broken structures and rejuvenate failing cells very effectively. Stem cell science has seen considerable advancements within the previous few years with several new developments and discoveries being created.
Swiss Medica Clinic has developed the Adult autologous stem cell medical care program to treat a range of conditions. Throughout stem cell treatment a patient receives 200 – 300 million stem cells. The number of restored cells not only covers daily losses, however exceeds them 1000 times. Thus, the reserve of the stem cells, much lost for the newest 15 – 20 years, is restored. When such active cell filling, organ gets rejuvenated and revived, because the new and active cells displace the previous and broken ones
Advanced Technologies to treat Diabetes
Diabetes is a serious condition which still doesn’t have a cure which makes new research, treatment and management techniques a crucial necessity. Over the past years there have been considerable breakthroughs in understanding and preventing diabetic complications. While some research focuses on generating artificial pancreas or engineering insulin-producing beta cells, some other researches are directed towards finding newer and longer lasting drug molecules, devising more efficient diets and also developing intensive treatment programs. Needless to say, trends and advances on diabetes research is the need of the hour for bringing about excellent management of this serious life-threatening disease.
Biomarker for Diabetes
Molecular Biomarkers can be demarcated as “a characteristic that is accurately measured and gauged as an pointer of normal biological procedures, pathogenic procedures, or pharmacologic responses to a pharmaceutical intervention. Biomarkers play a vital part in leading clinical trials and treating patients. Advances in molecular diagnostics help medical professionals make knowledgeable, scientifically valid decisions. More well-organized discovery and usage of biomarkers in the growth of antidiabetes drugs will depend on accelerating our understanding of the pathogenesis of diabetes and specifically its macrovascular complications. Procedural improvements from other fields, especially cancer, are beginning to show the way towards better models of diabetes pathogenesis and molecular biomarker discovery.
Diabetic Foot & other related disorders
Often, raised blood glucose is capable of damaging the sensation in the feet, affecting blood circulation to the area without which there usually tends to be delay in healing of the cuts and sores. When these symptoms are kept untreated, various complications are likely to arise like foot ulcers, foot infections and foot deformation and might also lead to amputation. Therefore it is extremely necessary to take proper care of the foot, undergo regular foot examinations and keep diabetes under control.
Herbal Therapy for Diabetes
Herbal supplements and remedies are used for the treatment of diabetes and hormonal problems such as estrogen and progesterone levels and treatment for menopausal hormone imbalance, etc. These include:
- Capsaicin cream, a topical ointment made with cayenne, has been reported by some patients to help lower pain in the hands and feet from diabetic neuropathy.
- Evening primrose oil is thought to help diabetic nerve pain
- Ginkgo, garlic, holy basil leaves, fenugreek seeds, ginseng, and hawthorn are other herbals that have been promoted by some as remedies for diabetic symptoms.
Alternative treatments include Acupuncture, Natural Dietary Supplements, Plant Foods, Natural Remedies for endocrine disorders, Hormonal imbalance cure by medicinal plants, Effects of Herbals in Male impotence & female infertility, Herbals acts on adrenal glands, Support the Endocrine System with Adaptogen Herbs, Avoid Environmental Toxins
Innovations in Diabetes Research
- Engineered Beta Cells
- Artificial Pancreas
- Islet Neogenesis
- New Anti-Diabetic Drugs
- Intensive Combination Therapies
- Development of Diabetic Diet
Market Analysis of Diabetic Products
Diabetes care market encompasses of technologies, devices and therapeutics in relative to diabetes. There has been a substantial increase in the amount of diabetes cases internationally over the last few years. Currently, about millions of people are in misery because of obesity, which is a key reason for increase of diabetes in people. Key Players profiled in the report include Glaxosmithkline, Novo Nordisk, Roche, Medtronic and etc. Novo Nordisk is a leading global provider of diabetes products. The company also has a headship spot in hemostasis management, growth hormone therapy and hormone replacement therapy. The company progresses, manufactures and markets its medical devices and technologies to hospitals, doctors, researchers, scientists and patients in approximately 160 countries.